1. Bollerslev J, et al. European Society of Endocrinology Clinical Guideline: Treatment of chronic hypoparathyroidism in adults. Eur J Endocrinol. 2015 Aug;173(2):G1-20.
  2. Brandi ML, et al. Management of Hypoparathyroidism: Summary Statement and Guidelines. The Journal of Clinical Endocrinology & Metabolism. 2016 Jun 1;101(6):2273–83.
  3. Chen K, et al. Clinical burden and healthcare resource utilization among patients with chronic hypoparathyroidism, overall and by adequately vs not adequately controlled disease: a multi-country chart review. Journal of Medical Economics. 2019 Jun 17;22(11):1141–52.
  4. Mannstadt M, et al. Hypoparathyroidism. Nat Rev Dis Primers. 2017 Aug 31;3:17055.
  5. Clarke BL, et al. Epidemiology and Diagnosis of Hypoparathyroidism. J Clin Endocrinol Metab. 2016 Jun 1;101(6):2284–2299.
  6. Khan AA, et al. Standards of care for hypoparathyroidism in adults: a Canadian and International Consensus. Eur J Endocrinol. 2019 Mar 01;180(3):1-22.
  7. Ascendis Pharma UK. Data on file. 2025.
  8. Shoback DM, et al. J Clin Endocrinol Metab. 2016;101(6):2300–12.
  9. National Cancer Institute. Bone Density. Available from: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/bone-density. [accessed October 2025].
  10. Medline Plus. Calcification. Available from: https://medlineplus.gov/ency/article/002321.htm [accessed October 2025].
  11. National Cancer Institute. Cognitive impairment. Available from: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/cognitive-impairment. [accessed October 2025].
  12. Institute of Medicine. Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: The National Academies Press; 2011.
  13. Qadeer HA, Bashire K. Physiology, Phosphate. StatPearls. 2020. Available from: https://www.ncbi.nlm.nih.gov/books/NBK560925/. [accessed October 2025].
  14. Goyal A, et al. Hypocalcemia. StatPearls. 2020. Available from: https://www.ncbi.nlm.nih.gov/books/NBK430912/. [accessed October 2025].
  15. Goyal R, Jialal I. Hyperphosphatemia. StatPearls. 2023. Available from: https://www.ncbi.nlm.nih.gov/books/NBK551586/. [accessed October 2025].
  16. National Cancer Institute. Renal Failure. Available from: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/renal-failure. [accessed October 2025].
  17. Brod M, et al. Living with hypoparathyroidism: development of the Hypoparathyroidism Patient Experience Scale-Impact (HPES-Impact). Qual Life Res. 2021 Jan;30(1):277-291. doi: 10.1007/s11136-020-02607-1. Epub 2020 Aug 24. PMID: 32833143; PMCID: PMC7847873.
  18. Kontogeorgos G, et al. Low health-related quality of life in hypoparathyroidism and need for PTH analog. Endocrine Connections. 2022 Jan 10;11(1).
  19. Ascendis Pharma UK. Data on file. 2024.

Find out more

Want to find out more?

Stay informed about the launch of the Hypopara Butterfly and other Seeds of Change initiatives across the UK!

Enter your contact details to receive updates.