References

Bollerslev J, et al. European Society of Endocrinology Clinical Guideline: Treatment of chronic hypoparathyroidism in adults. Eur J Endocrinol. 2015 Aug;173(2):G1-20.

Brandi ML, et al. Management of Hypoparathyroidism: Summary Statement and Guidelines. The Journal of Clinical Endocrinology & Metabolism. 2016 Jun 1;101(6):2273–83.

Chen K, et al. Clinical burden and healthcare resource utilization among patients with chronic hypoparathyroidism, overall and by adequately vs not adequately controlled disease: a multi-country chart review. Journal of Medical Economics. 2019 Jun 17;22(11):1141–52.

Mannstadt M, et al. Hypoparathyroidism. Nat Rev Dis Primers. 2017 Aug 31;3:17055.

Clarke BL, et al. Epidemiology and Diagnosis of Hypoparathyroidism. J Clin Endocrinol Metab. 2016 Jun 1;101(6):2284–2299.

Khan AA, et al. Standards of care for hypoparathyroidism in adults: a Canadian and International Consensus. Eur J Endocrinol. 2019 Mar 01;180(3):1-22.

Karpf D, et al. Prevalence of hypoparathyroidism in the EU: A systematic review and meta-analysis. Endocrine Abstracts. 2020;70:AEP140.

Shoback DM, et al. J Clin Endocrinol Metab. 2016;101(6):2300–12.

National Cancer Institute. Bone Density. Available from: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/bone-density. [accessed October 2025].

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Institute of Medicine. Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: The National Academies Press; 2011.

Qadeer HA, Bashire K. Physiology, Phosphate. StatPearls. 2020. Available from: https://www.ncbi.nlm.nih.gov/books/NBK560925/. [accessed October 2025].

Goyal A, et al. Hypocalcemia. StatPearls. 2020. Available from: https://www.ncbi.nlm.nih.gov/books/NBK430912/. [accessed October 2025].

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Brod M, et al. Living with hypoparathyroidism: development of the Hypoparathyroidism Patient Experience Scale-Impact (HPES-Impact). Qual Life Res. 2021 Jan;30(1):277-291. doi: 10.1007/s11136-020-02607-1. Epub 2020 Aug 24. PMID: 32833143; PMCID: PMC7847873.

Kontogeorgos G, et al. Low health-related quality of life in hypoparathyroidism and need for PTH analog. Endocrine Connections. 2022 Jan 10;11(1).

Hypopara overview

² Brandi ML, et al. Management of Hypoparathyroidism: Summary Statement and Guidelines. The Journal of Clinical Endocrinology & Metabolism. 2016 Jun 1;101(6):2273–83.

⁴ Mannstadt M, et al. Hypoparathyroidism. Nat Rev Dis Primers. 2017 Aug 31;3:17055.

⁸ Shoback DM, et al. J Clin Endocrinol Metab. 2016;101(6):2300-12.

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August 2025 | GL-COMMPTH-2500042

Support materials

We’re here to help navigate life with hypoparathyroidism. By providing the tools for self-advocacy, we empower those living with hypopara to take control of their care and champion a better quality of life.

Support materials

Improving understanding of hypoparathyroidism

Seeds of Change aims to support and empower people with hypoparathyroidism (also known as hypopara), so they are ready to advocate for improved care and quality of life.

The materials below are intended to help improve understanding and support patients, their loved ones, caregivers, and healthcare professionals in having meaningful discussions around hypopara care.

Tab 1 content.

Tab 2 content.

Useful tools

Managing the fluctuating symptoms, physical fatigue, and emotional strain of hypopara can make routine activities unpredictable.

Explore the resources below to help you or your loved ones to plan and participate in daily life.

Tool

New!

Symptom Butterfly Generator

Create your own symptom butterfly that uniquely represents your experience of living with hypopara.

FEATURES

✓ Share the butterfly with your doctor to support a discussion about your experiences

✓ Share your butterfly on social media to raise awareness and connect with others

Generate your butterfly

May 2026 | GL-COMMPTH-2600065

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Hypopara overview

View the symptoms of hypoparathyroidism in a visual aid.

FEATURES

✓ Visual symptom diagram

✓ Overview of key symptoms

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August 2025 | GL-COMMPTH-2500042

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Hypopara fact sheet

Discover more about the impact of hypoparathyroidism and its impact on quality of life.

FEATURES

✓ Quality of life insights

✓ Prevalence overview

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August 2025 | GL-COMMPTH-2500043

Tool

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Symptom Diary

If you have been diagnosed with hypoparathyroidism, you can use this digital diary to keep a track of your daily symptoms. You can also use a downloadable pdf version to support discussions with your doctor.

FEATURES

✓ Daily symptom capture

✓ A dashboard summary of your entries

Start tracking Download PDF

June 2026 | GL-COMMPTH-2600050

Download support materials

Click below to download hypoparathyroidism materials

Fact sheet with symptom diagram

Hypoparathyroidism

Prevalence, symptoms, and impact on quality of life.

August 2025
GL-COMMPTH-2500042

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Fact sheet without symptom diagram

Hypoparathyroidism

Prevalence and impact on quality of life.

August 2025
GL-COMMPTH-2500043

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Patient diary tool

Hypoparathyroidism

If you have been diagnosed with hypoparathyroidism, you can use this diary to keep a daily record to help you track your symptoms.

November 2025
GL-COMMPTH-2500052

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Our partners

We’re proud to work alongside Parathyroid UK and the Society for Endocrinology to support those living with hypoparathyroidism. Discover more about each of our partners below.